DNA elongation by the human DNA polymerase lambda polymerase and terminal transferase activities are differentially coordinated by proliferating cell nuclear antigen and replication protein A.

DNA polymerase lambda contains template-dependent (DNA polymerase) and template-independent (terminal transferase) activities. In this study we enzymologically characterized the terminal transferase activity of polymerase lambda (pol lambda-tdt). Pol lambda-tdt activity was strongly influenced by th...

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Bibliographic Details
Main Authors: Maga, G, Ramadan, K, Locatelli, G, Shevelev, I, Spadari, S, Hübscher, U
Format: Journal article
Language:English
Published: 2005