DNA elongation by the human DNA polymerase lambda polymerase and terminal transferase activities are differentially coordinated by proliferating cell nuclear antigen and replication protein A.

DNA elongation by the human DNA polymerase lambda polymerase and terminal transferase activities are differentially coordinated by proliferating cell nuclear antigen and replication protein A.

DNA polymerase lambda contains template-dependent (DNA polymerase) and template-independent (terminal transferase) activities. In this study we enzymologically characterized the terminal transferase activity of polymerase lambda (pol lambda-tdt). Pol lambda-tdt activity was strongly influenced by th...

Cur síos iomlán

Sonraí bibleagrafaíochta
Príomhchruthaitheoirí:	Maga, G, Ramadan, K, Locatelli, G, Shevelev, I, Spadari, S, Hübscher, U
Formáid:	Journal article
Teanga:	English
Foilsithe / Cruthaithe:	2005

Míreanna comhchosúla

De novo DNA synthesis by human DNA polymerase lambda, DNA polymerase mu and terminal deoxyribonucleotidyl transferase.
de réir: Ramadan, K, et al.
Foilsithe / Cruthaithe: (2004)

Mutagenesis of human DNA polymerase lambda: essential roles of Tyr505 and Phe506 for both DNA polymerase and terminal transferase activities.
de réir: Shevelev, I, et al.
Foilsithe / Cruthaithe: (2003)

Human DNA polymerase lambda possesses terminal deoxyribonucleotidyl transferase activity and can elongate RNA primers: implications for novel functions.
de réir: Ramadan, K, et al.
Foilsithe / Cruthaithe: (2003)

DNA polymerase lambda from calf thymus preferentially replicates damaged DNA.
de réir: Ramadan, K, et al.
Foilsithe / Cruthaithe: (2002)

Human DNA polymerase lambda diverged in evolution from DNA polymerase beta toward specific Mn(++) dependence: a kinetic and thermodynamic study.
de réir: Blanca, G, et al.
Foilsithe / Cruthaithe: (2003)

Human DNA polymerase lambda functionally and physically interacts with proliferating cell nuclear antigen in normal and translesion DNA synthesis.
de réir: Maga, G, et al.
Foilsithe / Cruthaithe: (2002)

Human DNA polymerases lambda and beta show different efficiencies of translesion DNA synthesis past abasic sites and alternative mechanisms for frameshift generation.
de réir: Blanca, G, et al.
Foilsithe / Cruthaithe: (2004)

DNA polymerase theta purified from human cells is a high-fidelity enzyme.
de réir: Maga, G, et al.
Foilsithe / Cruthaithe: (2002)

DNA polymerases and diseases
de réir: Ramadan, K, et al.
Foilsithe / Cruthaithe: (2007)

Inhibition of mammalian DNA polymerases by resveratrol: mechanism and structural determinants.
de réir: Locatelli, G, et al.
Foilsithe / Cruthaithe: (2005)

The human DNA polymerase lambda interacts with PCNA through a domain important for DNA primer binding and the interaction is inhibited by p21/WAF1/CIP1.
de réir: Maga, G, et al.
Foilsithe / Cruthaithe: (2004)

The DNA-polymerase-X family: controllers of DNA quality?
de réir: Ramadan, K, et al.
Foilsithe / Cruthaithe: (2004)

The TREX2 3'-->5' exonuclease physically interacts with DNA polymerase delta and increases its accuracy.
de réir: Shevelev, I, et al.
Foilsithe / Cruthaithe: (2002)

Replicative DNA polymerase mutations in cancer.
de réir: Heitzer, E, et al.
Foilsithe / Cruthaithe: (2014)

Replicative DNA polymerase mutations in cancer
de réir: Heitzer, E, et al.
Foilsithe / Cruthaithe: (2014)

Silencing of human DNA polymerase λ causes replication stress and is synthetically lethal with an impaired S phase checkpoint.
de réir: Zucca, E, et al.
Foilsithe / Cruthaithe: (2013)

Isw1 chromatin remodeling ATPase coordinates transcription elongation and termination by RNA polymerase II.
de réir: Morillon, A, et al.
Foilsithe / Cruthaithe: (2003)

Frequent exchange of the DNA polymerase during bacterial chromosome replication
de réir: Beattie, T, et al.
Foilsithe / Cruthaithe: (2017)

Regulation of eukaryotic DNA replication: genome architecture and polymerase switching
de réir: Oldach, P
Foilsithe / Cruthaithe: (2021)

UBR5 interacts with the replication fork and protects DNA replication from DNA polymerase η toxicity
de réir: Cipolla, L, et al.
Foilsithe / Cruthaithe: (2019)

A cell-cycle-dependent DNA polymerase activity that replicates intact DNA in chromatin.
de réir: Jackson, D, et al.
Foilsithe / Cruthaithe: (1986)

Defects in replicative DNA polymerases linked to cancer predisposition and tumour development
de réir: Bertrand, S
Foilsithe / Cruthaithe: (2020)

Distinct pools of proliferating cell nuclear antigen associated to DNA replication sites interact with the p125 subunit of DNA polymerase delta or DNA ligase I.
de réir: Riva, F, et al.
Foilsithe / Cruthaithe: (2004)

Expression of the cancer-associated DNA polymerase ε P286R in fission yeast leads to translesion synthesis polymerase dependent hypermutation and defective DNA replication
de réir: Soriano, I, et al.
Foilsithe / Cruthaithe: (2021)

Regulation of oxidative DNA damage repair by DNA polymerase λ and MutYH by cross-talk of phosphorylation and ubiquitination.
de réir: Markkanen, E, et al.
Foilsithe / Cruthaithe: (2012)

Tenofovir prodrugs potently inhibit Epstein–Barr virus lytic DNA replication by targeting the viral DNA polymerase
de réir: Drosu, Natalia C, et al.
Foilsithe / Cruthaithe: (2021)

Inhibition of hepatitis B virus DNA replication by imino sugars without the inhibition of the DNA polymerase: therapeutic implications.
de réir: Mehta, A, et al.
Foilsithe / Cruthaithe: (2001)

Influenza virus inhibits RNA polymerase II elongation.
de réir: Chan, A, et al.
Foilsithe / Cruthaithe: (2006)

Mcm10 regulates DNA replication elongation by stimulating the CMG replicative helicase
de réir: Looke, Marko, et al.
Foilsithe / Cruthaithe: (2017)

DNA polymerases beta and lambda mediate overlapping and independent roles in base excision repair in mouse embryonic fibroblasts
de réir: Braithwaite, Elena K., et al.
Foilsithe / Cruthaithe: (2011)

Y-family DNA polymerases in Escherichia coli
de réir: Jarosz, Daniel F., et al.
Foilsithe / Cruthaithe: (2012)

SnapShot: DNA Polymerases I Prokaryotes
de réir: Foti, James J., et al.
Foilsithe / Cruthaithe: (2014)

Fixing the model for transcription: the DNA moves, not the polymerase.
de réir: Papantonis, A, et al.
Foilsithe / Cruthaithe: (2011)

SnapShot: DNA Polymerases II Mammals
de réir: Foti, James J., et al.
Foilsithe / Cruthaithe: (2014)

Biological relevance of DNA polymerase β and translesion synthesis polymerases to cancer and its treatment.
de réir: Nicolay, N, et al.
Foilsithe / Cruthaithe: (2012)

Biological relevance of DNA polymerase beta and translesion synthesis polymerases to cancer and its treatment
de réir: Nicolay, N, et al.
Foilsithe / Cruthaithe: (2012)

Role of the RNA/DNA kinase Grc3 in transcription termination by RNA polymerase I.
de réir: Braglia, P, et al.
Foilsithe / Cruthaithe: (2010)

Transcription reinitiation by recycling RNA polymerase that diffuses on DNA after releasing terminated RNA
de réir: Kang, W, et al.
Foilsithe / Cruthaithe: (2020)

Nutritional Control of Elongation of DNA Replication by (p)ppGpp
de réir: Wang, Jue D., et al.
Foilsithe / Cruthaithe: (2014)

Significance of DNA polymerase I in in vivo processing of clustered DNA damage
de réir: Shikazono, N, et al.
Foilsithe / Cruthaithe: (2013)