Deficits in dopaminergic transmission precede neuron loss and dysfunction in a new Parkinson model.

The pathological end-state of Parkinson disease is well described from postmortem tissue, but there remains a pressing need to define early functional changes to susceptible neurons and circuits. In particular, mechanisms underlying the vulnerability of the dopamine neurons of the substantia nigra p...

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Xehetasun bibliografikoak
Egile Nagusiak: Janezic, S, Threlfell, S, Dodson, P, Dowie, M, Taylor, T, Potgieter, D, Parkkinen, L, Senior, S, Anwar, S, Ryan, B, Deltheil, T, Kosillo, P, Cioroch, M, Wagner, K, Ansorge, O, Bannerman, D, Bolam, J, Magill, P, Cragg, S, Wade-Martins, R
Formatua: Journal article
Hizkuntza:English
Argitaratua: National Academy of Sciences 2013