Deficits in dopaminergic transmission precede neuron loss and dysfunction in a new Parkinson model.
The pathological end-state of Parkinson disease is well described from postmortem tissue, but there remains a pressing need to define early functional changes to susceptible neurons and circuits. In particular, mechanisms underlying the vulnerability of the dopamine neurons of the substantia nigra p...
| Príomhchruthaitheoirí: | , , , , , , , , , , , , , , , , , , , |
|---|---|
| Formáid: | Journal article |
| Teanga: | English |
| Foilsithe / Cruthaithe: |
National Academy of Sciences
2013
|