Synthesis and biological evaluation of novel eunicellin analogues

The intramolecular Diels-Alder reaction of a 2,9-disubstituted hexahydro-Δ 5.6-oxonin derivative 14 afforded two diastereomeric tricyclic eunicellin analogues 15 and 16, which were desilylated to produce the alcohols 17 and 3; these were found to be microtubule stabilising ag...

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Bibliographic Details
Main Authors: Gilmour, R, Davidson, J, Burton, J, Holmes, AB
Format: Conference item
Published: 2005