Use of an outbred rat hepacivirus challenge model for design and evaluation of efficacy of different immunization strategies for hepatitis C virus

Use of an outbred rat hepacivirus challenge model for design and evaluation of efficacy of different immunization strategies for hepatitis C virus

<p><strong>Background and Aims:</strong>&nbsp;The lack of immunocompetent small animal models for hepatitis C virus (HCV) has greatly hindered the development of effective vaccines. Using rodent hepacivirus (RHV), a homolog of HCV that shares many characteristics of HCV infecti...

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Bibliographic Details
Main Authors: Atcheson, E, Li, W, Bliss, C, Chinnakannan, S, Heim, K, Sharpe, H, Hutchings, C, Dietrich, I, Nguyen, D, Kapoor, A, Jarvis, M, Klenerman, P, Barnes, E, Simmonds, P
Format: Journal article
Language:English
Published: Wiley 2019

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