Frequency and prognostic impact of antibodies to aquaporin-4 in patients with optic neuritis.

BACKGROUND: Antibodies to aquaporin-4 (AQP4-Ab) are found in 60-80% of patients with neuromyelitis optica (NMO), a severely disabling inflammatory CNS disorder of putative autoimmune aetiology, which predominantly affects the optic nerves and spinal cord. OBJECTIVE: To assess the frequency of AQP4-...

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Main Authors: Jarius, S, Frederikson, J, Waters, P, Paul, F, Akman-Demir, G, Marignier, R, Franciotta, D, Ruprecht, K, Kuenz, B, Rommer, P, Kristoferitsch, W, Wildemann, B, Vincent, A
格式: Journal article
语言:English
出版: 2010