Brain mechanisms associated with depressive relapse and associated cognitive impairment following acute tryptophan depletion.
BACKGROUND: Acute tryptophan depletion lowers brain serotonin synthesis and results in a transient, but striking, clinical relapse in recovered depressed patients. AIMS: To identify brain regions which change their activity as an acute depressive relapse evolves and to determine how pathological moo...
Main Authors: | Smith, K, Morris, J, Friston, K, Cowen, P, Dolan, R |
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Format: | Journal article |
Language: | English |
Published: |
1999
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