A gamma34.5 mutant of herpes simplex 1 causes severe inflammation in the brain.

A number of viral vectors are currently being evaluated as potential gene therapy vectors for gene delivery to the brain. As well as evaluating their ability to express a transgene for extended periods of time it is also essential to examine any cytotoxic immune response to such vectors as this may...

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Bibliographic Details
Main Authors: McMenamin, M, Byrnes, A, Charlton, H, Coffin, R, Latchman, D, Wood, M
Format: Journal article
Language:English
Published: 1998