A gamma34.5 mutant of herpes simplex 1 causes severe inflammation in the brain.
A number of viral vectors are currently being evaluated as potential gene therapy vectors for gene delivery to the brain. As well as evaluating their ability to express a transgene for extended periods of time it is also essential to examine any cytotoxic immune response to such vectors as this may...
Հիմնական հեղինակներ: | McMenamin, M, Byrnes, A, Charlton, H, Coffin, R, Latchman, D, Wood, M |
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Ձևաչափ: | Journal article |
Լեզու: | English |
Հրապարակվել է: |
1998
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Նմանատիպ նյութեր
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Potential and limitations of a gamma 34.5 mutant of herpes simplex 1 as a gene therapy vector in the CNS.
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The Herpes Simplex Virus Neurovirulence Factor γ34.5: Revealing Virus-Host Interactions.
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Early virion-associated suppression of cellular protein synthesis by herpes simplex virus is accompanied by inactivation of mRNA.
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Role of T cells in inflammation caused by adenovirus vectors in the brain.
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