A gamma34.5 mutant of herpes simplex 1 causes severe inflammation in the brain.
A number of viral vectors are currently being evaluated as potential gene therapy vectors for gene delivery to the brain. As well as evaluating their ability to express a transgene for extended periods of time it is also essential to examine any cytotoxic immune response to such vectors as this may...
Main Authors: | McMenamin, M, Byrnes, A, Charlton, H, Coffin, R, Latchman, D, Wood, M |
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Format: | Journal article |
Language: | English |
Published: |
1998
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