Immunization with a lentivector that targets tumor antigen expression to dendritic cells induces potent CD8+ and CD4+ T-cell responses.

Lentivectors stimulate potent immune responses to antigen transgenes and are being developed as novel genetic vaccines. To improve safety while retaining efficacy, we constructed a lentivector in which transgene expression was restricted to antigen-presenting cells using the mouse dectin-2 gene prom...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों: Lopes, L, Dewannieux, M, Gileadi, U, Bailey, R, Ikeda, Y, Whittaker, C, Collin, M, Cerundolo, V, Tomihari, M, Ariizumi, K, Collins, M
स्वरूप: Journal article
भाषा:English
प्रकाशित: 2008