Validation of Recently Proposed Colorectal Cancer Susceptibility Gene Variants in an Analysis of Families and Patients-a Systematic Review.

High-throughput sequencing analysis has accelerated searches for genes associated with risk for colorectal cancer (CRC); germline mutations in NTHL1, RPS20, FANCM, FAN1, TP53, BUB1, BUB3, LRP6, and PTPN12 have been recently proposed to increase CRC risk. We attempted to validate the association betw...

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Detalhes bibliográficos
Principais autores: Broderick, P, Dobbins, S, Chubb, D, Kinnersley, B, Dunlop, M, Tomlinson, I, Houlston, R
Formato: Journal article
Idioma:English
Publicado em: Elsevier 2016