Validation of Recently Proposed Colorectal Cancer Susceptibility Gene Variants in an Analysis of Families and Patients-a Systematic Review.

High-throughput sequencing analysis has accelerated searches for genes associated with risk for colorectal cancer (CRC); germline mutations in NTHL1, RPS20, FANCM, FAN1, TP53, BUB1, BUB3, LRP6, and PTPN12 have been recently proposed to increase CRC risk. We attempted to validate the association betw...

Full description

Bibliographic Details
Main Authors: Broderick, P, Dobbins, S, Chubb, D, Kinnersley, B, Dunlop, M, Tomlinson, I, Houlston, R
Format: Journal article
Language:English
Published: Elsevier 2016