A modified density gradient proteomic-based method to analyze endolysosomal proteins in cardiac tissue
The importance of lysosomes in cardiac physiology and pathology is well established, and evidence for roles in calcium signaling is emerging. We describe a label-free proteomics method suitable for small cardiac tissue biopsies based on density-separated fractionation, which allows study of endolyso...
Main Authors: | , , , , , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
Elsevier
2021
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