Electric-field-driven translocation of ssDNA through hydrophobic nanopores

The accurate sequencing of DNA using nanopores requires control over the speed of DNA translocation through the pores and also of the DNA conformation. Our studies show that ssDNA translocates through hourglass-shaped pores with hydrophobic constriction regions when an electric field is applied. The...

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Autori principali: Haynes, T, Smith, I, Wallace, E, Trick, J, Sansom, M, Khalid, S
Natura: Journal article
Pubblicazione: American Chemical Society 2018