CRISPR-Cas9 causes chromosomal instability and rearrangements in cancer cell lines, detectable by cytogenetic methods

CRISPR-Cas9 has quickly become the method of choice for genome editing, with multiple publications describing technical advances and novel applications. It has been widely adopted as a tool for basic research and has significant translational and clinical potential. However, its usage has outpaced t...

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Bibliographic Details
Main Authors: Rayner, E, Durin, M, Thomas, R, Moralli, D, O'Cathail, S, Tomlinson, I, Green, C, Lewis, A
Format: Journal article
Language:English
Published: Mary Ann Liebert Inc. 2019