Evaluating selfish spermatogonial selection and its role in human disease

<p>The majority of de novo mutations originate in the paternal germline. Prior evidence has shown that a subset of activating mutations arise spontaneously within the spermatogonial stem cell (SSC) and can expand clonally along the length of a seminiferous tubule. This process, Selfish Spermat...

وصف كامل

التفاصيل البيبلوغرافية
المؤلف الرئيسي: Ralph, H
مؤلفون آخرون: Goriely, A
التنسيق: أطروحة
منشور في: 2018