The conserved protein Seb1 drives transcription termination by binding RNA polymerase II and nascent RNA

The conserved protein Seb1 drives transcription termination by binding RNA polymerase II and nascent RNA

AbstractTermination of RNA polymerase II (Pol II) transcription is an important step in the transcription cycle, which involves the dislodgement of polymerase from DNA, leading to release of a functional transcript. Recent studies have identified the key players required for this process and showed...

Volledige beschrijving

Bibliografische gegevens
Hoofdauteurs:	Wittmann, S, Renner, M, Watts, B, Adams, O, Huseyin, M, Baejen, C, El Omari, K, Kilchert, C, Heo, D, Kecman, T, Cramer, P, Grimes, J, Vasiljeva, L, Vasilieva, L
Formaat:	Journal article
Gepubliceerd in:	Nature Publishing Group 2017

Gelijkaardige items

Profiling RNA polymerase II phosphorylation genome-wide in fission yeast
door: Kecman, T, et al.
Gepubliceerd in: (2018)

DSIF factor Spt5 coordinates transcription, maturation and exoribonucleolysis of RNA polymerase II transcripts
door: Kuś, K, et al.
Gepubliceerd in: (2025)

The regulation and functions of the nuclear RNA exosome complex
door: Kilchert, C, et al.
Gepubliceerd in: (2016)

DSIF factor Spt5 coordinates transcription, maturation and exoribonucleolysis of RNA polymerase II transcripts
door: Krzysztof Kuś, et al.
Gepubliceerd in: (2025-01-01)

lncRNA recruits RNAi and the exosome to dynamically regulate pho1 expression in response to phosphate levels in fission yeast.
door: Shah, S, et al.
Gepubliceerd in: (2014)

mRNA quality control goes transcriptional.
door: Kilchert, C, et al.
Gepubliceerd in: (2013)

System-wide analyses of the fission yeast poly(A)+ RNA interactome reveal insights into organisation and function of RNA-protein complexes
door: Kilchert, C, et al.
Gepubliceerd in: (2020)

Human Pcf11 enhances degradation of RNA polymerase II-associated nascent RNA and transcriptional termination.
door: West, S, et al.
Gepubliceerd in: (2008)

Human Pcf11 enhances degradation of RNA polymerase II-associated nascent RNA and transcriptional termination
door: West, S, et al.
Gepubliceerd in: (2008)

Investigating the role of Dis2 phosphatase in RNA Polymerase II transcription termination in fission yeast
door: Kecman, T
Gepubliceerd in: (2018)

Transcription termination and RNA degradation contribute to silencing of RNA polymerase II transcription within heterochromatin.
door: Vasiljeva, L, et al.
Gepubliceerd in: (2008)

Regulation of mRNA levels by decay-promoting introns that recruit the exosome specificity factor Mmi1
door: Kilchert, C, et al.
Gepubliceerd in: (2015)

AT-rich sequence elements promote nascent transcript cleavage leading to RNA polymerase II termination.
door: White, E, et al.
Gepubliceerd in: (2013)

The conserved RNA-binding protein Seb1 promotes cotranscriptional ribosomal RNA processing by controlling RNA polymerase I progression
door: Maxime Duval, et al.
Gepubliceerd in: (2023-05-01)

The Nrd1-Nab3-Sen1 termination complex interacts with the Ser5-phosphorylated RNA polymerase II C-terminal domain.
door: Vasiljeva, L, et al.
Gepubliceerd in: (2008)

Regulation of mRNA Levels by Decay-Promoting Introns that Recruit the Exosome Specificity Factor Mmi1
door: Cornelia Kilchert, et al.
Gepubliceerd in: (2015-12-01)

RNA-dependent RNA polymerases of dsRNA bacteriophages.
door: Makeyev, E, et al.
Gepubliceerd in: (2004)

Numbers and organization of RNA polymerases, nascent transcripts, and transcription units in HeLa nuclei.
door: Jackson, D, et al.
Gepubliceerd in: (1998)

Numbers and organization of RNA polymerases, nascent transcripts, and transcription units in HeLa nuclei
door: Jackson, D, et al.
Gepubliceerd in: (1998)

Transcription termination by RNA Polymerase II
door: White, E
Gepubliceerd in: (2012)

The C-terminal priming domain is strongly associated with the main body of bacteriophage φ6 RNA-dependent RNA polymerase
door: Sarin, L, et al.
Gepubliceerd in: (2012)

The C-terminal priming domain is strongly associated with the main body of bacteriophage ϕ6 RNA-dependent RNA polymerase.
door: Sarin, L, et al.
Gepubliceerd in: (2012)

Landscape of transcription termination in Arabidopsis revealed by single-molecule nascent RNA sequencing
door: Weipeng Mo, et al.
Gepubliceerd in: (2021-11-01)

SR Proteins Collaborate with 7SK and Promoter-Associated Nascent RNA to Release Paused Polymerase
door: Ji, Xiong, et al.
Gepubliceerd in: (2015)

Elongation/termination factor exchange mediated by PP1 phosphatase orchestrates transcription termination
door: Kecman, T, et al.
Gepubliceerd in: (2018)

Crystal structure of the RNA-dependent RNA polymerase from influenza C virus.
door: Hengrung, N, et al.
Gepubliceerd in: (2015)

RNA-binding protein Mub1 and the nuclear RNA exosome act to fine-tune environmental stress response
door: Birot, A, et al.
Gepubliceerd in: (2021)

Disengaging polymerase: terminating RNA polymerase II transcription in budding yeast.
door: Mischo, H, et al.
Gepubliceerd in: (2013)

Genome-wide mapping of yeast RNA polymerase II termination.
door: Paul Schaughency, et al.
Gepubliceerd in: (2014-10-01)

Transcriptional termination signals for RNA polymerase II in fission yeast.
door: Birse, C, et al.
Gepubliceerd in: (1997)

Transcription reinitiation by recycling RNA polymerase that diffuses on DNA after releasing terminated RNA
door: Kang, W, et al.
Gepubliceerd in: (2020)

Structure of the RNA-dependent RNA polymerase P2 from the cystovirus φ8
door: Latimer-Smith, M, et al.
Gepubliceerd in: (2024)

Structural insights into RNA polymerases of negative-sense RNA viruses
door: te Velthius, AJW, et al.
Gepubliceerd in: (2021)

Multiple transcript cleavage precedes polymerase release in termination by RNA polymerase II.
door: Dye, M, et al.
Gepubliceerd in: (2001)

Initiation, extension, and termination of RNA synthesis by a paramyxovirus polymerase.
door: Paul C Jordan, et al.
Gepubliceerd in: (2018-02-01)

Structure of the RNA-dependent RNA polymerase P2 from the cystovirus φ8
door: Merlyn Latimer-Smith, et al.
Gepubliceerd in: (2024-10-01)

Terminal exon definition occurs cotranscriptionally and promotes termination of RNA polymerase II.
door: Dye, M, et al.
Gepubliceerd in: (1999)

CDK12 globally stimulates RNA polymerase II transcription elongation and carboxyl-terminal domain phosphorylation
door: Tellier, M, et al.
Gepubliceerd in: (2020)

Structural and functional characterization of the interaction between the influenza A virus RNA polymerase and the CTD of host RNA polymerase II
door: Keown, J, et al.
Gepubliceerd in: (2024)

A role for chromatin remodeling in transcriptional termination by RNA polymerase II.
door: Alén, C, et al.
Gepubliceerd in: (2002)