Kinetic and structural evidence of the alkenal/one reductase specificity of human ζ-crystallin.
Human ζ-crystallin is a Zn(2+)-lacking medium-chain dehydrogenase/reductase (MDR) included in the quinone oxidoreductase (QOR) family because of its activity with quinones. In the present work a novel enzymatic activity was characterized: the double bond α,β-hydrogenation of medium-chain 2-alkenals...
Autori principali: | Porté, S, Moeini, A, Reche, I, Shafqat, N, Oppermann, U, Farrés, J, Parés, X |
---|---|
Natura: | Journal article |
Lingua: | English |
Pubblicazione: |
2011
|
Documenti analoghi
Documenti analoghi
-
Kinetic and structural evidence of the alkenal/one reductase specificity of human ζ-crystallin.
di: Porté, S, et al.
Pubblicazione: (2011) -
BIOLOGICAL ROLE OF ALDO-KETO REDUCTASES IN RETINOIC ACID BIOSYNTHESIS AND SIGNALING
di: F. Xavier eRuiz, et al.
Pubblicazione: (2012-04-01) -
Substrate Specificity, Inhibitor Selectivity and Structure-Function Relationships of Aldo-Keto Reductase 1B15: A Novel Human Retinaldehyde Reductase.
di: Joan Giménez-Dejoz, et al.
Pubblicazione: (2015-01-01) -
Perspective on the Structural Basis for Human Aldo-Keto Reductase 1B10 Inhibition
di: Francesc Xavier Ruiz, et al.
Pubblicazione: (2021-12-01) -
Three-dimensional structure and enzymatic function of proapoptotic human p53-inducible quinone oxidoreductase PIG3.
di: Porté, S, et al.
Pubblicazione: (2009)