Foxn1 regulates in postnatal thymic epithelial cells key target genes essential for T cell development

Thymic epithelial cell differentiation, growth and function depend on the expression of the transcription factor Foxn1, however its target genes have never been physically identified. Using novel static and inducible genetic model systems and chromatin studies, we provide now a genome wi...

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Bibliographic Details
Main Authors: Žuklys, S, Handel, A, Zhanybekova, S, Govani, F, Keller, M, Maio, S, Mayer, C, Teh, H, Hafen, K, Gallone, G, Barthlott, T, Ponting, C, Hollander, G
Format: Journal article
Published: Nature Publishing Group 2016