Interactions Between a Voltage Sensor and a Toxin via Multiscale Simulations
Gating-modifier toxins inhibit voltage-gated ion channels by binding the voltage sensors (VS) and altering the energetics of voltage-dependent gating. These toxins are thought to gain access to the VS via the membrane (i.e., by partitioning from water into the membrane before binding the VS). We use...
| Prif Awduron: | , , |
|---|---|
| Fformat: | Journal article |
| Cyhoeddwyd: |
2010
|