Interleukin-2 can prevent and reverse antigen-induced unresponsiveness in cloned human T lymphocytes.

The exposure of human T-cell clones to supra-immunogenic concentrations of peptide antigen in the absence of accessory cells induces antigen-specific unresponsiveness. Using this model we have investigated the ability of cytokines to modulate the induction of, or reversal of, T-cell tolerance. Our f...

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Sonraí bibleagrafaíochta
Príomhchruthaitheoirí: Essery, G, Feldmann, M, Lamb, JR
Formáid: Journal article
Teanga:English
Foilsithe / Cruthaithe: 1988