Interleukin-2 can prevent and reverse antigen-induced unresponsiveness in cloned human T lymphocytes.
The exposure of human T-cell clones to supra-immunogenic concentrations of peptide antigen in the absence of accessory cells induces antigen-specific unresponsiveness. Using this model we have investigated the ability of cytokines to modulate the induction of, or reversal of, T-cell tolerance. Our f...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
1988
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