Interleukin-2 can prevent and reverse antigen-induced unresponsiveness in cloned human T lymphocytes.
The exposure of human T-cell clones to supra-immunogenic concentrations of peptide antigen in the absence of accessory cells induces antigen-specific unresponsiveness. Using this model we have investigated the ability of cytokines to modulate the induction of, or reversal of, T-cell tolerance. Our f...
Κύριοι συγγραφείς: | Essery, G, Feldmann, M, Lamb, JR |
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Μορφή: | Journal article |
Γλώσσα: | English |
Έκδοση: |
1988
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Παρόμοια τεκμήρια
Παρόμοια τεκμήρια
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Influence of antigen structure on the activation and induction of unresponsiveness in cloned human T lymphocytes.
ανά: Lamb, JR, κ.ά.
Έκδοση: (1986) -
Biochemical events initiated by exposure of human T lymphocyte clones to immunogenic and tolerogenic concentrations of antigen.
ανά: Zanders, E, κ.ά.
Έκδοση: (1985) -
Direct evaluation of antigen binding to human T lymphocyte clones: involvement of major histocompatibility complex products in antigen binding.
ανά: Zanders, E, κ.ά.
Έκδοση: (1984) -
Antigen-specific T cell unresponsiveness in cloned helper T cells mediated via the CD2 or CD3/Ti receptor pathways.
ανά: Lamb, JR, κ.ά.
Έκδοση: (1987) -
Epithelial cells expressing aberrant MHC class II determinants can present antigen to cloned human T cells.
ανά: Londei, M, κ.ά.
Έκδοση: (1984)