The use of phosphate bioisosteres in medicinal chemistry and chemical biology
Phosphate and pyrophosphate groups play a central role in cellular signalling and consequently are of great interest to both medicinal chemists and chemical biologists. However, the design of molecules that can interfere with phosphate-based processes is recognised as a significant challenge, especi...
| Main Authors: | , , , |
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| Format: | Journal article |
| Published: |
2012
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