Olanzapine activates the rat locus coeruleus: in vivo electrophysiology and c-Fos immunoreactivity.

BACKGROUND: Activation of central noradrenergic pathways by atypical antipsychotics has been hypothesized to play a role in their efficacy in treating the negative symptoms and cognitive impairment of schizophrenia. Because acute administration of the atypical antipsychotic olanzapine has been shown...

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Bibliographic Details
Main Authors: Dawe, G, Huff, K, Vandergriff, J, Sharp, T, O'Neill, M, Rasmussen, K
Format: Journal article
Language:English
Published: 2001