Olanzapine activates the rat locus coeruleus: in vivo electrophysiology and c-Fos immunoreactivity.
BACKGROUND: Activation of central noradrenergic pathways by atypical antipsychotics has been hypothesized to play a role in their efficacy in treating the negative symptoms and cognitive impairment of schizophrenia. Because acute administration of the atypical antipsychotic olanzapine has been shown...
Main Authors: | , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
2001
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