Epithelial IL-6 trans-signaling defines a new asthma phenotype with increased airway inflammation

Epithelial IL-6 trans-signaling defines a new asthma phenotype with increased airway inflammation

<h4>Background</h4> <p>Although several studies link high levels of IL-6 and soluble IL-6 receptor (sIL-6R) with asthma severity and decreased lung function, the role of IL-6 trans-signaling (IL-6TS) in asthma is unclear</p> <h4>Objective</h4> <p>To explore...

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Bibliographic Details
Main Authors: Jevnikar, Z, Östling, J, Ax, E, Calvén, J, Thörn, K, Israelsson, E, Öberg, L, Singhania, A, Lau, L, Wilson, S, Ward, J, Chauhan, A, Sousa, A, De Meulder, B, Loza, M, Baribaud, F, Sterk, P, Chung, K, Sun, K, Guo, Y, Adcock, I, Payne, D, Dahlen, B, Chanez, P, Shaw, D, Krug, N, Hohlfeld, J, Sandström, T, Djukanovic, R, James, A, Hinks, T, Howarth, P, Vaarala, O, van Geest, M, Olsson, H
Format: Journal article
Language:English
Published: Elsevier 2018

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