Epithelial IL-6 trans-signaling defines a new asthma phenotype with increased airway inflammation

Epithelial IL-6 trans-signaling defines a new asthma phenotype with increased airway inflammation

<h4>Background</h4> <p>Although several studies link high levels of IL-6 and soluble IL-6 receptor (sIL-6R) with asthma severity and decreased lung function, the role of IL-6 trans-signaling (IL-6TS) in asthma is unclear</p> <h4>Objective</h4> <p>To explore...

Bibliográfalaš dieđut
Váldodahkkit:	Jevnikar, Z, Östling, J, Ax, E, Calvén, J, Thörn, K, Israelsson, E, Öberg, L, Singhania, A, Lau, L, Wilson, S, Ward, J, Chauhan, A, Sousa, A, De Meulder, B, Loza, M, Baribaud, F, Sterk, P, Chung, K, Sun, K, Guo, Y, Adcock, I, Payne, D, Dahlen, B, Chanez, P, Shaw, D, Krug, N, Hohlfeld, J, Sandström, T, Djukanovic, R, James, A, Hinks, T, Howarth, P, Vaarala, O, van Geest, M, Olsson, H
Materiálatiipa:	Journal article
Giella:	English
Almmustuhtton:	Elsevier 2018

Geahča maid

IL-6 trans-signaling definesa new asthma phenotype associated with frequent exacerbations, increased airway inflammation and impaired epithelial integrity
Dahkki: Olsson, H, et al.
Almmustuhtton: (2018)

Multi-tissue transcriptomics delineates the diversity of airway T cell functions in asthma
Dahkki: Singhania, A, et al.
Almmustuhtton: (2017)

Correlation of eotaxin-3 gene expression and other IL-13-induced genes in patients with asthma
Dahkki: Couillard, S, et al.
Almmustuhtton: (2021)

Steroid-induced deficiency of mucosal-associated invariant T cells in the chronic obstructive pulmonary disease lung. Implications for nontypeable haemophilus influenzae infection
Dahkki: Hinks, T, et al.
Almmustuhtton: (2016)

A computational framework for complex disease stratification from multiple large-scale datasets.
Dahkki: De Meulder, B, et al.
Almmustuhtton: (2018)

Clinical and transcriptomic features of persistent exacerbation‐prone severe asthma in U‐BIOPRED cohort
Dahkki: Uruj Hoda, et al.
Almmustuhtton: (2022-04-01)

OnPLS-based multi-block data integration: a multivariate approach to interrogating biological interactions in asthma
Dahkki: Reinke, SN, et al.
Almmustuhtton: (2018)

Blood eosinophil count and airway epithelial transcriptome relationships in COPD versus asthma
Dahkki: George, L, et al.
Almmustuhtton: (2019)

I_MDS: an inflammatory bowel disease molecular activity score to classify patients with differing disease-driving pathways and therapeutic response to anti-TNF treatment.
Dahkki: Stelios Pavlidis, et al.
Almmustuhtton: (2019-04-01)

Systemic inflammatory profile and response to anti-tumor necrosis factor therapy in chronic obstructive pulmonary disease
Dahkki: Loza Matthew J, et al.
Almmustuhtton: (2012-02-01)

Haemophilus influenzae and Moraxella catarrhalis in sputum of severe asthma with inflammasome and neutrophil activation
Dahkki: Versi, Ali, et al.
Almmustuhtton: (2024)

The use of induced sputum in clinical trials.
Dahkki: Kips, J, et al.
Almmustuhtton: (2002)

Multidimensional endotyping in patients with severe asthma reveals inflammatory heterogeneity in matrix metalloproteinases and chitinase 3–like protein 1
Dahkki: Hinks, T, et al.
Almmustuhtton: (2016)

Globalisation of accounting standards and competitive posture of Indian companies
Dahkki: Monica Singhania, et al.
Almmustuhtton: (2011-01-01)

T2 and T17 cytokines alter the cargo and function of airway epithelium-derived extracellular vesicles
Dahkki: Elisabeth Ax, et al.
Almmustuhtton: (2020-06-01)

Clinical applications of assessment of airway inflammation using induced sputum.
Dahkki: Pavord, I, et al.
Almmustuhtton: (2002)

Yhteistyön mahdollisuudet – lukiokoulutukseen valmistava koulutus kielellistyvässä maailmassa
Dahkki: Heidi Vaarala
Almmustuhtton: (2018-10-01)

Small airways, big challenge
Dahkki: P.J. Sterk, et al.
Almmustuhtton: (2011-03-01)

Proteomic signatures of eosinophilic and neutrophilic asthma from serum and sputumResearch in context
Dahkki: Khezia Asamoah, et al.
Almmustuhtton: (2024-01-01)

Assessing the impact of tumor evolution on oncology drug development and commercialization
Dahkki: Sterk, Joseph P. (Sterk, Joseph Phillip)
Almmustuhtton: (2011)

Altered regulation and expression of genes by BET family of proteins in COPD patients.
Dahkki: Rajneesh Malhotra, et al.
Almmustuhtton: (2017-01-01)

Correction: Altered regulation and expression of genes by BET family of proteins in COPD patients.
Dahkki: Rajneesh Malhotra, et al.
Almmustuhtton: (2017-01-01)

Franc Jeza v Trstu
Dahkki: Ivo Jevnikar
Almmustuhtton: (2024-12-01)

Vloga političnih beguncev iz Slovenije pri oživljanju slovenstva v zamejstvu v Italiji
Dahkki: Ivo Jevnikar
Almmustuhtton: (2022-12-01)

Slovenki domovi v južni Ameriki
Dahkki: Martin Jevnikar
Almmustuhtton: (1996-01-01)

Supporting Safer Spaces: How School Administrators Shape the School Culture for Sexual and Gender Minority Students
Dahkki: Ariadne Jevnikar
Almmustuhtton: (2022-12-01)

Slovenska slovnica za Italijane Bruna Guyona
Dahkki: Jevnikar Martin
Almmustuhtton: (1972-02-01)

Gas production by Paucilactobacillus wasatchensis WDCO4 is increased in Cheddar cheese containing sodium gluconate
Dahkki: D.J. McMahon, et al.
Almmustuhtton: (2022-05-01)

Basic Online Pennsylvania Legal Research for Librarians
Dahkki: Laura J. Ax-Fultz
Almmustuhtton: (2014-05-01)

Using an electronic diary and wristband accelerometer to detect exacerbations and activity levels in COPD: a feasibility study
Dahkki: Lydia J. Finney, et al.
Almmustuhtton: (2023-12-01)

NEW FAMILY OF SUPERCONDUCTING COPPER OXIDES - GASR2LN1-XCAXCU2O7
Dahkki: Dabrowski, B, et al.
Almmustuhtton: (1992)

Treatment of COVID-19-exacerbated asthma: should systemic corticosteroids be used?
Dahkki: Kumar, K, et al.
Almmustuhtton: (2020)

Learning by imitation in games: theory, field, and laboratory
Dahkki: Mohlin, E, et al.
Almmustuhtton: (2014)

Biological functions of MAIT cells in tissues
Dahkki: Klenerman, P, et al.
Almmustuhtton: (2020)

Comparison of fMRI with the Wada test for lateralisation of language in pre-surgical epilepsy patients
Dahkki: Adcock, J, et al.
Almmustuhtton: (2001)

Functional magnetic resonance imaging: clinical applications and potential.
Dahkki: Matthews, P, et al.
Almmustuhtton: (1999)

5613475 ADVERSE REACTIONS TO RBC TRANSFUSION: A SINGLE THALASSEMIA AND SICKLE CELL DISEASE DEPARTMENT’S EXPERIENCE
Dahkki: A.X. Xydaki, et al.
Almmustuhtton: (2023-04-01)

Rhinovirus and dsRNA induce RIG-I-like receptors and expression of interferon β and λ1 in human bronchial smooth muscle cells.
Dahkki: Jenny Calvén, et al.
Almmustuhtton: (2013-01-01)

How effective are on-farm conservation land management strategies for preserving ecosystem services in developing countries? A systematic map protocol
Dahkki: Thorn, J, et al.
Almmustuhtton: (2015)

UTILIZACIÓN DE LAS MEDIDAS ZOOMÉTRICAS PARA PREDECIR EL PESO CORPORAL EN CABRAS CRIOLLAS, EN EL SUR DEL ESTADO DE MÉXICO
Dahkki: Dorantes C.E.J., et al.
Almmustuhtton: (2015-12-01)