Regulatory T cells promote apelin-mediated sprouting angiogenesis in type 2 diabetes

The role of CD4+ T cells in the ischemic tissues of T2D patients remains unclear. Here, we report that T2D patients' vascular density was negatively correlated with the number of infiltrating CD4+ T cells after ischemic injury. Th1 was the predominant subset, and Th1-derived IFN-γ and TNF-α dir...

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Bibliographic Details
Main Authors: Leung, O, Li, J, Li, X, Chan, V, Yang, K, Ku, M, Ji, L, Sun, H, Waldmann, H, Tian, X, Huang, Y, Lau, J, Zhou, B, Lui, K
Format: Journal article
Language:English
Published: Elsevier 2018