A hierarchical Bayesian model for understanding the spatiotemporal dynamics of the intestinal epithelium

Our work addresses two key challenges, one biological and one methodological. First, we aim to understand how proliferation and cell migration rates in the intestinal epithelium are related under healthy, damaged (Ara-C treated) and recovering conditions, and how these relations can be used to ident...

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Détails bibliographiques
Auteurs principaux: Maclaren, OJ, Parker, A, Pin, C, Carding, SR, Watson, AJM, Fletcher, AJ, Byrne, HM, Maini, PK
Format: Journal article
Publié: Public Library of Science 2017