A mechanistic investigation of the oxygen fixation hypothesis and oxygen enhancement ratio

The presence of oxygen in tumours has substantial impact on treatment outcome; relative to anoxic regions, well-oxygenated cells respond better to radiotherapy by a factor 2.5–3. This increased radio-response is known as the oxygen enhancement ratio. The oxygen effect is most commonly explained by t...

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Bibliographic Details
Main Authors: Grimes, D, Partridge, M
Format: Journal article
Published: IOP Science 2015