Dissection of agonistic and blocking effects of CD200 receptor antibodies

The CD200 receptor (CD200R) is present mainly on myeloid cells and gives inhibitory signals when engaged by its ligand CD200. The interaction is currently of therapeutic interest in cancer and inflammation. However functional effects are complicated by the fact that CD200R is itself polymorphic and...

Täydet tiedot

Bibliografiset tiedot
Päätekijät: Akkaya, M, Aknin, M, Akkaya, B, Barclay, N
Aineistotyyppi: Journal article
Kieli:English
Julkaistu: Public Library of Science 2013