Toenail selenium status and DNA repair capacity among female BRCA1 mutation carriers.

Selenium is an important cofactor of various antioxidant enzymes and has been shown to enhance DNA repair in normal human fibroblasts. Oral selenium supplementation has also been shown to decrease the number of chromosome breaks in BRCA1 mutation carriers. Because the predisposition to cancer among...

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Bibliographic Details
Main Authors: Kotsopoulos, J, Chen, Z, Vallis, K, Poll, A, Ghadirian, P, Kennedy, G, Ainsworth, P, Narod, SA
Format: Journal article
Language:English
Published: 2010