Dynamic sensitivity of ATP-sensitive K(+) channels to ATP.

ATP and MgADP regulate K(ATP) channel activity and hence potentially couple cellular metabolism to membrane electrical activity in various cell types. Using recombinant K(ATP) channels that lack sensitivity to MgADP, expressed in COSm6 cells, we demonstrate that similar on-cell activity can be obser...

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Bibliographic Details
Main Authors: Loussouarn, G, Pike, L, Ashcroft, F, Makhina, E, Nichols, C
Format: Journal article
Language:English
Published: 2001