Investigating the molecular mechanisms of recombination-dependent replication in fission yeast

<p>Perturbation of DNA replication is a major cause of cancer and other pathological states causing loss of genome integrity and catastrophic chromosomal rearrangements. To guard against such disaster, mechanisms exist to process and stabilize replication forks (RFs) blocked at barriers, resta...

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Bibliographic Details
Main Author: Ishnazarova, N
Other Authors: Whitby, M
Format: Thesis
Published: 2018