Characterization of Foxp3+CD4+CD25+ and IL-10-secreting CD4+CD25+ T cells during cure of colitis.

CD4+CD25+ regulatory T cells can prevent and resolve intestinal inflammation in the murine T cell transfer model of colitis. Using Foxp3 as a marker of regulatory T cell activity, we now provide a comprehensive analysis of the in vivo distribution of Foxp3+CD4+CD25+ cells in wild-type mice, and duri...

Full description

Bibliographic Details
Main Authors: Uhlig, H, Coombes, J, Mottet, C, Izcue, A, Thompson, C, Fanger, A, Tannapfel, A, Fontenot, J, Ramsdell, F, Powrie, F
Format: Journal article
Language:English
Published: 2006