Chromosome contacts in activated T cells identify autoimmune disease candidate genes

Autoimmune disease-associated variants are preferentially found in regulatory regions in immune cells, particularly CD4+ T cells. Linking such regulatory regions to gene promoters in disease-relevant cell contexts facilitates identification of candidate disease genes.Within 4 h, activation of CD4+ T...

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Bibliographic Details
Main Authors:	Burren, O, Rubio García, A, Javierre, B, Rainbow, D, Cairns, J, Cooper, N, Lambourne, J, Schofield, E, Castro Dopico, X, Ferreira, R, Coulson, R, Burden, F, Rowlston, S, Downes, K, Wingett, S, Frontini, M, Ouwehand, W, Fraser, P, Spivakov, M, Todd, J, Wicker, L, Cutler, A, Wallace, C
Format:	Journal article
Language:	English
Published:	BioMed Central 2017

Chromosome contacts in activated T cells identify autoimmune disease candidate genes

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