Structural and functional anatomy of the globular domain of complement protein C1q.

C1q is the first subcomponent of the classical pathway of the complement system and a major connecting link between innate and acquired immunity. As a versatile charge pattern recognition molecule, C1q is capable of engaging a broad range of ligands via its heterotrimeric globular domain (gC1q) whic...

Full description

Bibliographic Details
Main Authors: Kishore, U, Ghai, R, Greenhough, T, Shrive, A, Bonifati, D, Gadjeva, MG, Waters, P, Kojouharova, MS, Chakraborty, T, Agrawal, A
Format: Journal article
Language:English
Published: 2004