Arid5a: A missing link between EMT and tumoral immune resistance

Epithelial-to-mesenchymal transition (EMT) endows tumor cells with the ability to invade and migrate, and to suppress antitumor immunity. In this issue, Parajuli and colleagues report that EMT tumors often express the RNA-binding protein AT-rich interactive domain 5a (Arid5a), which they find stabil...

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Bibliographic Details
Main Author: Van den Eynde, BJ
Format: Journal article
Language:English
Published: American Association for Cancer Research 2021