Runx1 is required for progression of CD41+ embryonic precursors into HSCs but not prior to this.
Haematopoiesis in adult animals is maintained by haematopoietic stem cells (HSCs), which self-renew and can give rise to all blood cell lineages. The AGM region is an important intra-embryonic site of HSC development and a wealth of evidence indicates that HSCs emerge from the endothelium of the emb...
| Váldodahkkit: | , , , , , , , , , , |
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| Materiálatiipa: | Journal article |
| Giella: | English |
| Almmustuhtton: |
Company of Biologists Ltd
2014
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