A novel human leucocyte antigen-DRB1 genotyping method based on multiplex primer extension reactions.

We have developed and validated a semi-automated fluorescent method of genotyping human leucocyte antigen (HLA)-DRB1 alleles, HLA-DRB1*01-16, by multiplex primer extension reactions. This method is based on the extension of a primer that anneals immediately adjacent to the single-nucleotide polymorp...

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Bibliographic Details
Main Authors: Jaakkola, E, Herzberg, I, Crane, A, Pointon, J, Laiho, K, Kauppi, M, Kaarela, K, Wordsworth, B, Tuomilehto, J, Brown, M
Format: Journal article
Language:English
Published: 2004