A novel human leucocyte antigen-DRB1 genotyping method based on multiplex primer extension reactions.
We have developed and validated a semi-automated fluorescent method of genotyping human leucocyte antigen (HLA)-DRB1 alleles, HLA-DRB1*01-16, by multiplex primer extension reactions. This method is based on the extension of a primer that anneals immediately adjacent to the single-nucleotide polymorp...
Main Authors: | Jaakkola, E, Herzberg, I, Crane, A, Pointon, J, Laiho, K, Kauppi, M, Kaarela, K, Wordsworth, B, Tuomilehto, J, Brown, M |
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Format: | Journal article |
Language: | English |
Published: |
2004
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