α-amino aldehydes as readily available chiral aldehydes for Rh-catalyzed alkyne hydroacylation

Readily available α-amino aldehydes, incorporating a methylthiomethyl (MTM) protecting group on nitrogen, are shown to be efficient substrates in Rh-catalyzed alkyne hydroacylation reactions. The reactions are performed under mild conditions, employing a small-bite-angle bis-phosphine ligand, allowi...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों: Hooper, JF, Seo, S, Truscott, FR, Neuhaus, JD, Willis, MC
स्वरूप: Journal article
भाषा:English
प्रकाशित: American Chemical Society 2016