α-amino aldehydes as readily available chiral aldehydes for Rh-catalyzed alkyne hydroacylation

Readily available α-amino aldehydes, incorporating a methylthiomethyl (MTM) protecting group on nitrogen, are shown to be efficient substrates in Rh-catalyzed alkyne hydroacylation reactions. The reactions are performed under mild conditions, employing a small-bite-angle bis-phosphine ligand, allowi...

詳細記述

書誌詳細
主要な著者: Hooper, JF, Seo, S, Truscott, FR, Neuhaus, JD, Willis, MC
フォーマット: Journal article
言語:English
出版事項: American Chemical Society 2016