α-amino aldehydes as readily available chiral aldehydes for Rh-catalyzed alkyne hydroacylation
Readily available α-amino aldehydes, incorporating a methylthiomethyl (MTM) protecting group on nitrogen, are shown to be efficient substrates in Rh-catalyzed alkyne hydroacylation reactions. The reactions are performed under mild conditions, employing a small-bite-angle bis-phosphine ligand, allowi...
| Main Authors: | , , , , |
|---|---|
| Format: | Journal article |
| Jezik: | English |
| Izdano: |
American Chemical Society
2016
|