Characterization of the flexible lip regions in bacteriophage lambda lysozyme using MD simulations

The upper and lower lip regions in lysozyme from bacteriophage lambda (λ-lysozyme) are flexible in solution and exhibit two different conformations in crystal structures of the protein. MD simulations have been used to characterize the structure and dynamics of these lip regions, which surround the...

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Bibliographic Details
Main Authors: Smith, L, van Gunsteren, W, Hansen, N
Format: Journal article
Language:English
Published: Springer 2015