Plasmodium falciparum antigenic variation: relationships between widespread endothelial activation, parasite PfEMP1 expression and severe malaria.

Plasmodium falciparum antigenic variation: relationships between widespread endothelial activation, parasite PfEMP1 expression and severe malaria.

BACKGROUND: Plasmodium falciparum erythrocyte membrane protein 1(PfEMP1) is a family of variant surface antigens (VSA) that mediate the adhesion of parasite infected erythrocytes to capillary endothelial cells within host tissues. Opinion is divided over the role of PfEMP1 in the widespread endothel...

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Détails bibliographiques
Auteurs principaux:	Abdi, A, Fegan, G, Muthui, M, Kiragu, E, Musyoki, J, Opiyo, M, Marsh, K, Warimwe, G, Bull, P
Format:	Journal article
Langue:	English
Publié:	BioMed Central 2014

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