Plasmodium falciparum antigenic variation: relationships between widespread endothelial activation, parasite PfEMP1 expression and severe malaria.
BACKGROUND: Plasmodium falciparum erythrocyte membrane protein 1(PfEMP1) is a family of variant surface antigens (VSA) that mediate the adhesion of parasite infected erythrocytes to capillary endothelial cells within host tissues. Opinion is divided over the role of PfEMP1 in the widespread endothel...
主要な著者: | Abdi, A, Fegan, G, Muthui, M, Kiragu, E, Musyoki, J, Opiyo, M, Marsh, K, Warimwe, G, Bull, P |
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フォーマット: | Journal article |
言語: | English |
出版事項: |
BioMed Central
2014
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