Plasmodium falciparum antigenic variation: relationships between widespread endothelial activation, parasite PfEMP1 expression and severe malaria.

Plasmodium falciparum antigenic variation: relationships between widespread endothelial activation, parasite PfEMP1 expression and severe malaria.

BACKGROUND: Plasmodium falciparum erythrocyte membrane protein 1(PfEMP1) is a family of variant surface antigens (VSA) that mediate the adhesion of parasite infected erythrocytes to capillary endothelial cells within host tissues. Opinion is divided over the role of PfEMP1 in the widespread endothel...

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Detalhes bibliográficos
Principais autores:	Abdi, A, Fegan, G, Muthui, M, Kiragu, E, Musyoki, J, Opiyo, M, Marsh, K, Warimwe, G, Bull, P
Formato:	Journal article
Idioma:	English
Publicado em:	BioMed Central 2014

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